Vitamin Supplements for Drug-Induced Depletion

Did you know certain medications can affect how your body absorbs nutrients?  Taking regular medications can also cause shortages of important vitamins your body needs.  See the chart below to find out which nutrients your medication may be depleting.  

Chart of Drug-Induced Nutrient Depletion

Medicines always have some side effects, and while generally benign, nutrient depletion isn’t something you have to live with.  Through vitamin and multivitamin supplements, you can increase the amount of nutrients your body is getting despite the effects of your regular medication.  Taking supplements to counter drug-induced depletion can help you feel better and stave off potential health problems.

Consult the chart below to see what supplements are best for you based on the medications you are taking.

 

Medication

Nutrients Depleted

Supplement Suggestions

NSAIDs

aspirin, celecoxib (Celebrex), diclofenac (Voltaren), ibuprofen (Motrin), ketorolac (Toradol), naproxen (Aleve, Naprosyn)

Folic Acid, Vitamin C, Iron
  • Alpha Base Multivitamin with Iron

Opiates

hydrocodone (Vicodin), morphine (MS Contin, Kadian), oxycodone (Oxycontin, Percoset)

Folic Acid, Vitamin C, Iron, Potassium
  • Alpha Base Multivitamin with Iron

Beta-2 Adrenergic Receptor Agonists

proventil (Albuterol), fluticasone+salmeterol (Advair), bitolterol (Tornalate), levalbuterol (Xopenex)

Potassium, Calcium, Magnesium
  • Reacted Multimin

Antibiotics

Levaquin, Avelox, Ciprofloxacin, Noroxin, Trovan, Amoxicillin, Amoxil, Trimox, Penicillin, Erythromycin, Azithromycin, Biaxin, Zithromax

Biotin, B1, B2, B3, B6, B12, Zinc, Calcium, Magnesium, Potassium, Vitamin K, Healthy Intestinal Bacteria

Option 1:

  • Reacted Multimin
  • Ortho B Complex or Methyl B Complex
  • Ortho Biotic

Option 2:

  • Alpha Base Multivitamin
  • Ortho Biotic

Conjugated Estrogens

Premarin, Premprop, Oral Contraceptives, Estrace

B6, B12, Vitamin D, Calcium, Magnesium, Zinc, Folic Acid

Option 1:

  • Reacted Multimin
  • Ortho B Complex or Methyl B Complex
  • Vitamin D3 5000IU

Option 2:

  • Alpha Base Multivitamin

Bio-Identical Hormones

Estradiol, Estriol, Estrone

B6, B12, Vitamin D, Calcium, Magnesium, Zinc, Folic Acid

Option 1:

  • Reacted Multimin
  • Ortho B Complex or Methyl B Complex
  • Vitamin D3 5000IU

Option 2:

  • Alpha Base Multivitamin
  • Ortho Biotic

Corticosteroids

betamethasone (Celestone, Soluspan), hydrocortisone (Cortef), prednisone (Rayos, Sterapred)

Beta-Carotene, B6, Folic Acid, Vitamin C, Vitamin D, Calcium, Magnesium
  • Alpha Base Multivitamin
  • Reacted Multimin

Loop Diuretics

bumetanide (Bumex), furosemide (Lasix), ethacrynate (Edecrin)

B1, B6, Vitamin C, Calcium, Magnesium, Zinc, Potassium

Option 1:

  • Ortho B Complex or Methyl B Complex
  • Reacted Multimin

Option 2:

  • Alpha Base Multivitamin

Thiazide Diuretics

chlorthalidone (Hygroton), indapamide (Lozol), hydrochlorothiazide (Hydrodiuril), methyclothiazide (Enduron)

Magnesium, B1, B6, Phosphorous, Potassium, Zinc, Coenzyme Q10

Option 1:

  • Reacted Multimin
  • CoQ-10 100mg or CoQ-10 300mg
  • Ortho B Complex or Methyl B Complex

Option 2:

  • Alpha Base Multivitamin
  • CoQ-10 100mg or CoQ-10 300mg

Potassium Sparing Diuretics

Amiloride hydrochloride, spironolactone (Aldactone), triamterene (Dyrenium)

Calcium, Magnesium
  • Reacted Cal-Mag

Laxatives with Bisacodyl

Dulcolax, Correctol, Feen-a-Mint, Carter’s Little Pills

Calcium, Potassium
  • Reacted Multimin

Statins

atorvastatin (Lipitor), fluvastatin (Lescol), lovastatin (Mevacor, Altocor), pravastatin (Pravachol), rosuvastatin (Crestor) simvastatin (Zocor)

Coenzyme Q10
  • CoQ-10 100mg or CoQ-10 300mg

ACE Inhibitors

captopril (Capoten), enalapril (Vasotec), lisinopril (Prinivil, Zestril), quinapril (Accupril), ramipril (Altace)

Zinc
  • Reacted Multimin

Beta Blockers

atenolol (Tenormin), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), carvedilol (Coreg)

Coenzyme Q10
  • CoQ-10 100mg or CoQ-10 300mg

Calcium Channel Blockers

amlodipine (Norvasc) felodipine (Plendil) nifedipine (Procardia, Adalat) nimodipine (Nimotop), nisoldipine (Sular)

Vitamin D
  • Vitamin D3 5000IU

Cardiac Glycosides

digoxin (Lanoxin, Digitek)

Magnesium, Potassium

Option 1:

  • Reacted Multimin

Option 2:

  • Alpha Base Multivitamin

Potassium Supplements

potassium chloride (Klor-Con)

B12
  • Methyl B12

Biguanides

metaformin (Glucophage)

Folic Acid, B12

Option 1:

  • Ortho B Complex or Methyl B Complex

Option 2:

  • Methyl B12

Sulfonylureas

glyburide (Diabeta, Glynase Micronase), glipizide (GlipiZIDE XL, Glucotrol), glimepiride (Amaryl)

Healthy Intestinal Bacteria, Coenzyme Q10
  • CoQ-10 100mg or CoQ-10 300mg
  • Ortho Biotic

H2 Inhibitors

famotidine (Pepcid), cimetidine (Tagamet), ranitidine (Zantac)

Folic Acid, B12, Vitamin D, Calcium, Iron, Zinc

Option 1:

  • Reacted Multimin
  • Ortho B Complex or Methyl B Complex
  • Vitamin D3 5000IU

Option 2:

  • Alpha Base Multivitamin

Proton-Pump Inhibitors

omeprazole (Prilosec, Zegerid), lansoprazole (Prevacid), esomeprazole (Nexium), rabeprazole (Aciphex)

Beta-Carotene, B12, Folic Acid, Calcium, Zinc, Iron

Option 1:

  • Reacted Multimin
  • Ortho B Complex or Methyl B Complex

Option 2:

  • Alpha Base Multivitamin

Antacids

Amphojel, Basaljel, Aluminum Hydroxide plus Magnesium, Gaviscon-2, Gelusil, Maalox, Mylanta

Folic Acid, Vitamin D, Zinc, Calcium, Magnesium, Chromium, Iron

Option 1:

  • Reacted Multimin
  • Ortho B Complex or Methyl B Complex
  • Vitamin D3 5000IU

Option 2:

  • Alpha Base Multivitamin

Antidepressants

clomipramine (Anafranil), amoxapine (Asendin), doxepin HCL (Sinequon), imipramine (Tofranil)

Coenzyme Q10, Vitamin B2
  • CoQ-10 100mg or CoQ-10 300mg
  • Ortho B Complex or Methyl B Complex

Bisphosphonates

alendronate (Fosamax), risedronate (Actonel), ibandronate (Boniva), etidronate (Didronel) zoledronic acid (Reclast)

Calcium, Magnesium
  • Reacted Cal-Mag

Vitamin Supplements FAQs

 faWhat’s the difference between a vitamin and a multivitamin? 

The only difference between a vitamin and a multivitamin is that a multivitamin contains more than on particular vitamin or nutrient.  A vitamin will be something specific, like Vitamin B12.  A multivitamin contains a variety of vitamins in a single pill.  You could take multiple vitamin pills, but it can be easier to find a multivitamin that includes everything you need in a single dose.

Do I need a prescription for vitamin or multivitamin supplements?

There are prescription vitamins and multivitamins, but most are available over-the-counter without a prescription.  Prenatal vitamins and folic acid supplements will typically require a prescription, as well as higher doses of more common vitamins like Vitamin D.  You can always talk to your doctor about whether a prescription supplement would be necessary.

Why do we need vitamins?

The human body requires a variety of nutrients to perform all its basic functions.  Different parts of the body might require different nutrients to grow and to perform their biological tasks.  A deficiency of certain nutrients can cause health problems and even lead to death.  Scurvy is one such example of a disease caused by the lack of Vitamin C.  These conditions are rarer today with greater access to food and with modern foods having more diverse nutrients included in them.  While food sciences have made searching out specific vitamins and nutrients less important these days, people can still suffer from deficiencies for a variety of reasons.  Certain illnesses may affect a person’s ability to effectively absorb some nutrients, and modern medicines often have side effects that can cause nutrient deficiencies.  This is referred to as “drug-induced deficiency”.  Since people need these medicines to deal with serious health conditions, they will often look to supplements as a way of getting more of the vitamins and nutrients they need to make up for the effects of their medication. 

Do vitamins cause weight gain?

Vitamins cannot directly cause weight gain.  Generally vitamins have no calories.  However, some may contain a small number of calories depending on their delivery mechanism.  For example, sweet vitamin gummies contain mostly sugar and can have around 15 calories per gummy.  This is still too little calories to have a meaningful effect on a person’s weight, however.

Is it possible to overdose on vitamins?

It is possible to overdose on vitamins, but would typically require taking very large quantities of vitamin supplements.  Most symptoms of taking too many vitamins are not particularly severe, but there are some very rare cases of people dying from vitamin overdoses.  Usually side effects of getting too much of a particular vitamin includes nausea, diarrhea, stomach cramps or fatigue. 

There is very little risk of getting too much of a vitamin through eating normal meals.  Very high dosages would be needed to cause health issues.  When taking supplements, be sure to follow the recommended doses and keep bottles out of reach of children.  

 

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